Published Papers

List of Published Papers

Functional capillary impairment in patients with ventricular assist devices.
Sci Rep. 2019 Apr 11;9(1):5909. doi: 10.1038/s41598-019-42334-3.


Early Onset Preeclampsia Is Associated With Glycocalyx Degradation and Reduced Microvascular Perfusion.
J Am Heart Assoc. 2019 Feb 19;8(4):e010647. doi: 10.1161/JAHA.118.010647.


Alterations of conjunctival glycocalyx and microcirculation in non-septic critically ill patients
Microvasc Res. 2018 Jul;118:44-48. doi: 10.1016/j.mvr.2018.02.004. Epub 2018 Feb 17.


Automated Measurement of Microvascular Function Reveals Dysfunction in Systemic Sclerosis: A Cross-sectional Study.
J Rheumatol. 2017 Nov;44(11):1603-1611. doi: 10.3899/jrheum.170120. Epub 2017 Sep 15.


Advanced age results in a diminished endothelial glycocalyx.
Am J Physiol Heart Circ Physiol. 2018 Sep 1;315(3):H531-H539. doi: 10.1152/ajpheart.00104.2018. Epub 2018 May 11.


Induced Trf2 deletion leads to aging vascular phenotype in mice associated with arterial telomere uncapping, senescence signaling, and oxidative stress.
J Mol Cell Cardiol. 2019 Feb;127:74-82. doi: 10.1016/j.yjmcc.2018.11.014. Epub 2018 Nov 29.


Impact of Intravenous Fluid Challenge Infusion Time on Macrocirculation and Endothelial Glycocalyx in Surgical and Critically Ill Patients.
Biomed Res Int. 2018 Nov 1;2018:8925345. doi: 10.1155/2018/8925345. eCollection 2018.


Neuraxial anesthesia is less harmful to the endothelial glycocalyx during elective joint surgery compared to general anesthesia1,2.
Clin Hemorheol Microcirc. 2018 Nov 29. doi: 10.3233/CH-180428. [Epub ahead of print]


Effect of acute hypernatremia induced by hypertonic saline administration on endothelial glycocalyx in rabbits.
Clin Hemorheol Microcirc. 2018 Nov 2. doi: 10.3233/CH-189907. [Epub ahead of print]


The Effect of Fluid Loading and Hypertonic Saline Solution on Cortical Cerebral Microcirculation and Glycocalyx Integrity.
J Neurosurg Anesthesiol. 2018 Jul 13. doi: 10.1097/ANA.0000000000000528. [Epub ahead of print]


Increase in perfused boundary region of endothelial glycocalyx is associated with higher prevalence of ischemic heart disease and lesions of microcirculation and vascular wall.
Microcirculation. 2018 May;25(4):e12454. doi: 10.1111/micc.12454.


In vivo assessment of the human cerebral microcirculation and its glycocalyx: A technical report.
J Neurosci Methods. 2018 Jun 1;303:114-125. doi: 10.1016/j.jneumeth.2018.03.009. Epub 2018 Mar 22.


HDL cholesterol levels and endothelial glycocalyx integrity in treated hypertensive patients.
J Clin Hypertens (Greenwich). 2018 Nov;20(11):1615-1623. doi: 10.1111/jch.13404. Epub 2018 Oct 13.


Association of impaired endothelial glycocalyx with arterial stiffness, coronary microcirculatory dysfunction, and abnormal myocardial deformation in untreated hypertensives.
J Clin Hypertens (Greenwich). 2018 Apr;20(4):672-679. doi: 10.1111/jch.13236. Epub 2018 Mar 2.


Sublingual functional capillary rarefaction in chronic heart failure.
Eur J Clin Invest. 2018 Feb;48(2). doi: 10.1111/eci.12869. Epub 2017 Dec 14.


Bedside analysis of the sublingual microvascular glycocalyx in the emergency room and intensive care unit – the GlycoNurse study.
Scand J Trauma Resusc Emerg Med. 2018 Feb 14;26(1):16. doi: 10.1186/s13049-018-0483-4.


The Measurement of the Endothelial Glycocalyx as a New Biomarker of Endothelial Derangement in Systemic Sclerosis: A Challenge for the Future.
J Rheumatol. 2017 Nov;44(11):1572-1574. doi: 10.3899/jrheum.170958. Epub 2017 Nov 1. No abstract available.


Automated Measurement of Microvascular Function Reveals Dysfunction in Systemic Sclerosis: A Cross-sectional Study.
J Rheumatol. 2017 Nov;44(11):1603-1611. doi: 10.3899/jrheum.170120. Epub 2017 Sep 15.


Non-invasive assessment of microvascular dysfunction in patients with microvascular angina.
Int J Cardiol. 2017 Dec 1;248:433-439. doi: 10.1016/j.ijcard.2017.05.010. Epub 2017 Jul 18.


Effects of varenicline and nicotine replacement therapy on arterial elasticity, endothelial glycocalyx and oxidative stress during a 3-month smoking cessation program.
Atherosclerosis. 2017 May 13;262:123-130.


Protocol for intraoperative assessment of the human cerebrovascular glycocalyx.
BMJ Open. 2017 Jan 5;7(1)


Early detection of left ventricular dysfunction in first-degree relatives of diabetic patients by myocardial deformation imaging: The role of endothelial glycocalyx damage.
Int J Cardiol. 2017 Apr 15;233:105-112.


Side-by-Side Alterations in Glycocalyx Thickness and Perfused Microvascular Density During Acute Microcirculatory Alterations in Cardiac Surgery.
Microcirculation. 2016 Jan;23(1):69-74.


Improvement of arterial stiffness and myocardial deformation in patients with poorly controlled diabetes mellitus type 2 after optimization of antidiabetic medication.
Eur Heart J Cardiovasc Imaging. 2016 Dec 1;17(suppl_2)


The impact of periodontal disease treatment on endothelium of sublingual microvessels.
Stomatologiia (Mosk). 2016;95(4):9-12. Russian.


Perturbation of the microvascular glycocalyx and perfusion in infants after cardiopulmonary bypass.
J Thorac Cardiovasc Surg. 2015 Dec;150(6):1474-81.


Plasma free hemoglobin and microcirculatory response to fresh or old blood transfusions in sepsis.
PLoS One. 2015 May 1;10(5):e0122655


Characteristics and determinants of the sublingual microcirculation in populations of different ethnicity.
Hypertension. 2015 May;65(5):993-1001


Effects of ultrapure hemodialysis and low molecular weight heparin on the endothelial surface layer.
Blood Purif. 2014;38(3-4):203-10


Is the systemic microvascular endothelial glycocalyx in peritoneal dialysis patients related to peritoneal transport?
Nephron ClinPract. 2014;128(1-2):159-65


Deeper penetration of erythrocytes into the endothelial glycocalyx is associated with impaired microvascular perfusion.
PLoS One. 2014 May 9;9(5):e96477


Skeletal muscle capillary density and microvascular function are compromised with aging and type 2 diabetes.
J ApplPhysiol (1985). 2014 Apr 15;116(8):998-1005 


Microcirculatory effects of the transfusion of leukodepleted or non-leukodepleted red blood cells in patients with sepsis: a pilot study.
Crit Care. 2014 Feb 17;18(1):R33


Association of kidney function with changes in the endothelial surface layer.
Clin J Am SocNephrol. 2014 Apr;9(4):698-704


Alteration of the sublingual microvascular glycocalyx in critically ill patients.
Microvasc Res. 2013 Nov;90:86-9


Non-invasive assessment of microvascular dysfunction in families with premature coronary artery disease.
Int J Cardiol. 2013 Oct 12;168(5):5026-8


Sublingual microvascular glycocalyx dimensions in lacunar stroke patients.
Cerebrovasc Dis. 2013;35(5):451-4


Damage of the endothelial glycocalyx in dialysis patients.
J Am SocNephrol. 2012 Nov;23(11):1900-8


Methods for evaluating endothelial function: a position statement from the European Society of Cardiology Working Group on Peripheral Circulation.
Eur J Cardiovasc PrevRehabil. 2011 Dec;18(6):775-89


Effect of sulodexide on endothelial glycocalyx and vascular permeability in patients with type 2 diabetes mellitus.
Diabetologia. 2010 Dec;53(12):2646-55


Acute ischemic injury to the renal microvasculature in human kidney transplantation.
Am J Physiol Renal Physiol. 2010 Nov;299(5):F1134-40



Request Demonstration

Contact MicroVascular Health Solutions, the exclusive worldwide distributor of GlycoCheck, for a demonstration.

Request Demonstration





Email Opt-in

Stay up to date on the latest developments about the glycocalyx and GlycoCheck. Please opt in to receive email updates.   

Subscribe to our mailing list

* indicates required